Non-alcoholic Fatty Liver Disease and Alcoholic Liver Disease

Posted On 2020-07-15 03:58:19


Alcohol-associated liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are commonest causes of chronic liver disease. In spite of different risk factor, they share common spectrum of fatty liver/steatosis, steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. However, these two diseases are different on many aspects. With the progress made over the last decade, Translational Gastroenterology and Hepatology feels the need for reviewing the latest updates and identify unmet needs with future prospects on ALD and NAFLD. It is my privilege to guest edit this focused issue, with contributions on various aspects by experts in the respective field.

Editorial
Similarities and differences between non-alcoholic fatty liver disease (NAFLD) & alcohol-associated liver disease (ALD)
Ashwani K. Singal

Review Article
Epidemiology of non-alcoholic and alcoholic fatty liver diseases
Souveek Mitra, Arka De, Abhijit Chowdhury

Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD)
Narendra Singh Choudhary, Ajay Duseja

Pathogenesis and pathways: nonalcoholic fatty liver disease & alcoholic liver disease
Kyle E. Robinson, Vijay H. Shah

Gut microbiome changes in Nonalcoholic fatty liver disease & alcoholic liver disease
Eric K. Kwong, Puneet Puri

Mitochondrial dysfunction in nonalcoholic fatty liver disease and alcohol related liver disease
Pankaj Prasun, Ilona Ginevic, Kimihiko Oishi

Clinical presentation of alcoholic liver disease and non-alcoholic fatty liver disease: spectrum and diagnosis
Praveen Sharma, Anil Arora

Effect of alcohol consumption on nonalcoholic fatty liver disease
Gong Weng, Winston Dunn

Nonalcoholic fatty liver disease and alcoholic liver disease: metabolic diseases with systemic manifestations
Alexander J. Kovalic, George Cholankeril, Sanjaya K. Satapathy

Non-invasive diagnosis: non-alcoholic fatty liver disease and alcoholic liver disease
Jose Altamirano, Qiaochu Qi, Sabina Choudhry, Mohamed Abdallah, Ashwani K. Singal, Abhinav Humar, Ramón Bataller, Amir Ali Borhani, Andrés Duarte-Rojo

Acute on chronic liver failure in non-alcoholic fatty liver and alcohol associated liver disease
Ashwani K. Singal, Patrick S. Kamath

Hepatocellular carcinoma in alcoholic and non-alcoholic fatty liver disease—one of a kind or two different enemies?
Christine Pocha, Chencheng Xie

Emerging medical therapies for non-alcoholic fatty liver disease and for alcoholic hepatitis
Vincent Wai-Sun Wong, Ashwani K. Singal

Basic science to clinical trials in non-alcoholic fatty liver disease and alcohol-related liver disease: collaboration with industry
Amon Asgharpour, Amreen Dinani, Scott L. Friedman

Original Article
Cholecystectomy does not worsen progression or outcomes in non-alcoholic fatty liver disease
Souveek Mitra, Arka De, Abhijit Chowdhury

Disclosure:
The series “Non-alcoholic Fatty Liver Disease and Alcoholic Liver Disease” was commissioned by the editorial office, Translational Gastroenterology and Hepatology without any sponsorship or funding. Ashwani K. Singal served as the unpaid Guest Editor for the series.