Liver transplantation for hilar cholangiocarcinoma (h-CCA): is it the right time?

Liver transplantation (LT) is the therapy of choice in selected patients with hepatocellular carcinoma (HCC). In light of the overall excellent results achieved for HCC, LT has been successfully adapted as a therapeutic option for several non-hepatocellular malignancies (1) including unresectable hepatic epithelioid hemangioendothelioma (HEHE) (2), neuroendocrine tumors (NET) (3) or even colorectal metastases in case of liver-only disease (4).