@article{TGH3714,
author = {Giuseppe Maria Ettorre and Giovanni Battista Levi Sandri and Marco Colasanti and Gianluca Mascianà and Edoardo de Werra and Roberto Santoro and Pasquale Lepiane and Marzia Montalbano and Mario Antonini and Giovanni Vennarecci},
title = {Liver resection for hepatocellular carcinoma ≥5 cm},
journal = {Translational Gastroenterology and Hepatology},
volume = {2},
number = {3},
year = {2017},
keywords = {},
abstract = {Background: Management of hepatocellular carcinoma (HCC) larger than 5 cm is still debated. The aim of our study was to compare morbidity and mortality after the surgical resection of HCC according to the nodule size.
Methods: Since 2001, 429 liver resections for HCC were performed in our institution. We divided the cohort into two groups, 88 patients in group 1 patients with HCC diameter from 5 to 10 cm and 39 patients in group 2 with HCC diameter ≥10 cm.
Results: In 30.7% of cases in the first group and in 35.9% of cases in the second group the HCC grew into a healthy liver. A major liver resection was performed in 36.3% of cases in group 1 vs. 66.6% in group 2 (P=0.001). In two cases for the first group and in ten cases in the second group a laparoscopic approach was performed. Median operative time was higher in group 2 (P=0.001). The median post-operative hospital stay was similar in the two groups (P=0.897). The post-operative morbidity was not different between the two groups (P=0.595).
Conclusions: The tumour size does not contraindicate a surgical resection of HCC even in patient with HCC ≥10 cm.},
issn = {2415-1289}, url = {https://tgh.amegroups.org/article/view/3714}
}